RetinSphere® Technology

Innovative technology that combines two high tolerance retinoids. Proven efficacy in acne-prone, photoaging and depigmenting skin care.


Retinoids are molecules derived from vitamin A or retinol, well known in dermatology for the treatment of acne, photoaging and hyperpigmentation thanks to its renewing action of the surface layers of the skin.

Its possible side effects (redness, irritation and flaking skin) prompted Cantabria Labs to develop a technology with high efficacy and well tolerated by the skin. Retinsphere® Technology has been shown to be effective in many studies for the care of acne-prone, pigmented and aging skin.


RetinSphere® Technology is the association of two stable, effective retinoids with excellent tolerability: hydroxypinacolone retinoate and stabilised and encapsulated retinol. This technology has similar efficacy to that of retinoic acid, but without its adverse effects.


Hydroxypinacolone retinoate

Retinoic acid derivative that gives the same renewing benefits of skin, but without its potential for irritation.

Stabilised and encapsulated retinol

This gradual release system facilitates the penetration of retinol into the deeper layers of the skin where it acts in a sustained way over time.

Mechanism of Action

Retinol is transformed into retinoic acid in the higher layers of the epidermis and acts on its cells, enhancing the process of natural skin renewal:

  • It promotes the growth and differentiation of cells to combat wrinkles, pigmentation and fine lines.
  • It inhibits the synthesis of tyrosinase, an enzyme responsible for the production of melanin, to reduce dark spots.
  • It normalizes the formation of the follicular epithelium so that it does not become clogged and lead to acne.



Tri Active Gel
Facial gel that prevents and reduces active lesions and blemishes in acne-prone skin.


Tri Active Spray
Body spray that prevents and reduces active lesions and scars in acne-prone skin.


Duo Anti-Blemish Gel
Facial gel with excellent tolerance, which prevents and reduces mild and moderate lesions in acne-prone skin.


Soothing Gel
Facial gel for the care and maintenance of optimal conditions in acne-prone skin.

NEORETIN Discrom Control

Ultra Emulsion
Intensive pigment lightening with a high concentration of lightening and anti-pollution

NEORETIN Discrom Control

Transition Cream
Soothing, moisturising skin lightening cream to renew skin barrier and assist in retinoid acclimation. All skin types, including sensitive.

NEORETIN Discrom Control

Serum Booster Fluid
Rapidly-absorbed serum with a high concentration of lightening active ingredients.

NEORETIN Discrom Control

Gelcream SPF 50
Light, rapidly-absorbed day cream with lightening active and high sun protection.

NEORETIN Discrom Control

Lightening Peel
Intensive exfoliant and lightening peel disks for periodic use.

Latest from Communication Area

News 30 Oct 2020

Cantabria Labs acquires the ELANCYL body care brand from Pierre Fabre

Spanish pharmaceutical company Cantabria Labs has bought ELANCYL, the expert body care brand, after reaching an acquisition agreement with the...
News 12 May 2020

Rafa Nadal with HELIOCARE: “Give your all for what matters never to the sun”

• The Spanish tennis ace is the face of the “Give Your All for What Matters never to the Sun”...
News 7 May 2020

Cantabria Labs collaborates in the Covid-19 research project of Alcalá University

The study led by the University Professor Melchor Álvarez de Mon, seeks to identify precisely which medicines and what treatments will...